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Rapid generation of clinical-grade antiviral T cells: selection of suitable T-cell donors and GMP-compliant manufacturing of antiviral T cells

BACKGROUND: The adoptive transfer of allogeneic antiviral T lymphocytes derived from seropositive donors can safely and effectively reduce or prevent the clinical manifestation of viral infections or reactivations in immunocompromised recipients after hematopoietic stem cell (HSCT) or solid organ tr...

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Detalles Bibliográficos
Autores principales: Tischer, Sabine, Priesner, Christoph, Heuft, Hans-Gert, Goudeva, Lilia, Mende, Wolfgang, Barthold, Marc, Kloeß, Stephan, Arseniev, Lubomir, Aleksandrova, Krasimira, Maecker-Kolhoff, Britta, Blasczyk, Rainer, Koehl, Ulrike, Eiz-Vesper, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335407/
https://www.ncbi.nlm.nih.gov/pubmed/25510656
http://dx.doi.org/10.1186/s12967-014-0336-5