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Roflumilast improves corticosteroid resistance COPD bronchial epithelial cells stimulated with toll like receptor 3 agonist

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterised by chronic pulmonary inflammation punctuated by periods of viral exacerbations. Recent evidence suggests that the combination of roflumilast with corticosteroids may improve the compromised anti-inflammatory properties of cort...

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Detalles Bibliográficos
Autores principales: Milara, Javier, Morell, Anselm, Ballester, Bea, Sanz, Celia, Freire, Jose, Qian, Xiaozhong, Alonso-Garcia, Maggie, Morcillo, Esteban, Cortijo, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335416/
https://www.ncbi.nlm.nih.gov/pubmed/25652132
http://dx.doi.org/10.1186/s12931-015-0179-5