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Inhibition of nucleoporin member Nup214 expression by miR-133b perturbs mitotic timing and leads to cell death
BACKGROUND: Nucleoporins mediate nucleocytoplasmic exchange of macromolecules and several have been assigned active mitotic functions. Nucleoporins can participate in various mitotic functions like spindle assembly, kinetochore organisation and chromosome segregation- important for genome integrity....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335456/ https://www.ncbi.nlm.nih.gov/pubmed/25743594 http://dx.doi.org/10.1186/s12943-015-0299-z |