Drosophila TIM Binds Importin α1, and Acts as an Adapter to Transport PER to the Nucleus

Regulated nuclear entry of clock proteins is a conserved feature of eukaryotic circadian clocks and serves to separate the phase of mRNA activation from mRNA repression in the molecular feedback loop. In Drosophila, nuclear entry of the clock proteins, PERIOD (PER) and TIMELESS (TIM), is tightly con...

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Detalles Bibliográficos
Autores principales: Jang, A. Reum, Moravcevic, Katarina, Saez, Lino, Young, Michael W., Sehgal, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335507/
https://www.ncbi.nlm.nih.gov/pubmed/25674790
http://dx.doi.org/10.1371/journal.pgen.1004974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335507/
https://www.ncbi.nlm.nih.gov/pubmed/25674790
http://dx.doi.org/10.1371/journal.pgen.1004974

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