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Screening of HaCaT Clones for CCL20 Gene Knockout and Preliminary Exploration of Gene-Targeting Vector Transfection Approaches in this Cell Line

BACKGROUND: Inhibition of CC chemokine ligand 20 (CCL20), which is expressed by human keratinocytes after proinflammatory cytokine stimulation, may reduce migration of recipient Langerhans cells into tissue-engineered allogeneic skin grafts and minimize immune rejection by the recipient. Here, we sc...

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Detalles Bibliográficos
Autores principales: Wang, Yong, Peng, Daizhi, Wang, Lihua, Dong, Zhengxue, He, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335591/
https://www.ncbi.nlm.nih.gov/pubmed/25672883
http://dx.doi.org/10.12659/MSMBR.893143