The role of the insulin-like growth factor-1 system in breast cancer

IGF-1 is a potent mitogen of major importance in the mammary gland. IGF-1 binding to the cognate receptor, IGF-1R, triggers a signaling cascade leading to proliferative and anti-apoptotic events. Although many of the relevant molecular pathways and intracellular cascades remain to be elucidated, a g...

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Detalles Bibliográficos
Autores principales: Christopoulos, Panagiotis F, Msaouel, Pavlos, Koutsilieris, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335664/
https://www.ncbi.nlm.nih.gov/pubmed/25743390
http://dx.doi.org/10.1186/s12943-015-0291-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335664/
https://www.ncbi.nlm.nih.gov/pubmed/25743390
http://dx.doi.org/10.1186/s12943-015-0291-7

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