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Wogonin modulates hydroperoxide-induced apoptosis via PI3K/Akt pathway in retinal pigment epithelium cells
BACKGROUND: Oxidative stress causes the defects of retinal pigment epithelial (RPE) cells that contribute to age-related macular degeneration (AMD). This study was conducted to determine whether wogonin could prevent H(2)O(2)-induced oxidative stress in RPE cells. METHODS: A RPE cell line, ARPE-19,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335665/ https://www.ncbi.nlm.nih.gov/pubmed/25432585 http://dx.doi.org/10.1186/s13000-014-0154-3 |