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Wogonin modulates hydroperoxide-induced apoptosis via PI3K/Akt pathway in retinal pigment epithelium cells

BACKGROUND: Oxidative stress causes the defects of retinal pigment epithelial (RPE) cells that contribute to age-related macular degeneration (AMD). This study was conducted to determine whether wogonin could prevent H(2)O(2)-induced oxidative stress in RPE cells. METHODS: A RPE cell line, ARPE-19,...

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Detalles Bibliográficos
Autores principales:	Yan, Tingqin, Bi, Hongsheng, Wang, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335665/ https://www.ncbi.nlm.nih.gov/pubmed/25432585 http://dx.doi.org/10.1186/s13000-014-0154-3

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