Transcription factor and microRNA interactions in lung cells: an inhibitory link between NK2 homeobox 1, miR-200c and the developmental and oncogenic factors Nfib and Myb

BACKGROUND: The transcription factor NK2 homeobox 1 (Nkx2-1) plays essential roles in epithelial cell proliferation and differentiation in mouse and human lung development and tumorigenesis. A better understanding of genes and pathways downstream of Nkx2-1 will clarify the multiple roles of this cri...

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Detalles Bibliográficos
Autores principales: Tagne, Jean-Bosco, Mohtar, Omar R, Campbell, Joshua D, Lakshminarayanan, Meenakshi, Huang, Jingshu, Hinds, Anne C, Lu, Jining, Ramirez, Maria I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335692/
https://www.ncbi.nlm.nih.gov/pubmed/25763778
http://dx.doi.org/10.1186/s12931-015-0186-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335692/
https://www.ncbi.nlm.nih.gov/pubmed/25763778
http://dx.doi.org/10.1186/s12931-015-0186-6

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