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Deficiency of fibroblast activation protein alpha ameliorates cartilage destruction in inflammatory destructive arthritis

INTRODUCTION: Inflammatory destructive arthritis, like rheumatoid arthritis (RA), is characterized by invasion of synovial fibroblasts (SF) into the articular cartilage and erosion of the underlying bone, leading to progressive joint destruction. Because fibroblast activation protein alpha (FAP) has...

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Detalles Bibliográficos
Autores principales: Wäldele, Stefan, Koers-Wunrau, Christina, Beckmann, Denise, Korb-Pap, Adelheid, Wehmeyer, Corinna, Pap, Thomas, Dankbar, Berno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335697/
https://www.ncbi.nlm.nih.gov/pubmed/25600705
http://dx.doi.org/10.1186/s13075-015-0524-6