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Deficiency of fibroblast activation protein alpha ameliorates cartilage destruction in inflammatory destructive arthritis
INTRODUCTION: Inflammatory destructive arthritis, like rheumatoid arthritis (RA), is characterized by invasion of synovial fibroblasts (SF) into the articular cartilage and erosion of the underlying bone, leading to progressive joint destruction. Because fibroblast activation protein alpha (FAP) has...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335697/ https://www.ncbi.nlm.nih.gov/pubmed/25600705 http://dx.doi.org/10.1186/s13075-015-0524-6 |