Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors

Direct reprogramming provides a fundamentally new approach for the generation of patient-specific cells. Here, by screening a pool of candidate transcription factors, we identify that a combination of three factors, MITF, SOX10 and PAX3, directly converts mouse and human fibroblasts to functional me...

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Detalles Bibliográficos
Autores principales: Yang, Ruifeng, Zheng, Ying, Li, Ling, Liu, Shujing, Burrows, Michelle, Wei, Zhi, Nace, Arben, Herlyn, Meenhard, Cui, Rutao, Guo, Wei, Cotsarelis, George, Xu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335710/
https://www.ncbi.nlm.nih.gov/pubmed/25510211
http://dx.doi.org/10.1038/ncomms6807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335710/
https://www.ncbi.nlm.nih.gov/pubmed/25510211
http://dx.doi.org/10.1038/ncomms6807

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