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Evaluation of the efficacy of intrathecal injection of amitriptyline and doxepin in spinal anesthesia in comparison with bupivacaine in rats

BACKGROUND: Tricyclic antidepressants (TCAs) are commonly used orally for treating chronic pain states, such as neuropathic pain. TCAs produce analgesia by various mechanisms, including sodium channels, N-methyl-d-aspartate receptors, biogenic amines, opioids, inflammatory mediators, and substance P...

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Detalles Bibliográficos
Autores principales: Alebouyeh, Mahmoud Reza, Imani, Farnad, Rahimzadeh, Poupak, Faiz, Seyyed Hamid Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335756/
https://www.ncbi.nlm.nih.gov/pubmed/25729650
http://dx.doi.org/10.5812/kowsar.22287523.1511