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Expression of TRF2 and its prognostic relevance in advanced stage cervical cancer patients

BACKGROUND: Telomeres are protective caps consisted of specific tandem repeats (5′-TTAGGG-3′). Shortening of telomeres at each cell division is known as “mitotic clock” of the cells, which renders telomeres as important regulators of lifespan. TRF2 is one of the critical members of shelterin complex...

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Detalles Bibliográficos
Autores principales: Ozden, Sevgi, Tiber, Pinar Mega, Ozgen, Zerrin, Ozyurt, Hazan, Serakinci, Nedime, Orun, Oya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335779/
https://www.ncbi.nlm.nih.gov/pubmed/25654471
http://dx.doi.org/10.1186/0717-6287-47-61