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Randomized study of teriflunomide effects on immune responses to neoantigen and recall antigens

OBJECTIVE: To evaluate immune responses to neoantigen and recall antigens in healthy subjects treated with teriflunomide. METHODS: This was a randomized, double-blind, placebo-controlled study. Subjects received oral teriflunomide (70 mg once daily for 5 days followed by 14 mg once daily for 25 days...

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Detalles Bibliográficos
Autores principales: Bar-Or, Amit, Wiendl, Heinz, Miller, Barry, Benamor, Myriam, Truffinet, Philippe, Church, Meg, Menguy-Vacheron, Francoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335822/
https://www.ncbi.nlm.nih.gov/pubmed/25738167
http://dx.doi.org/10.1212/NXI.0000000000000070