Thrombomodulin protects against lung damage created by high level of oxygen with large tidal volume mechanical ventilation in rats

BACKGROUND: Ventilator-induced lung injury (VILI) is associated with inflammatory responses in the lung. Thrombomodulin (TM), a component of the coagulation system, has anticoagulant and anti-inflammatory effects. We hypothesized that the administration of recombinant human soluble TM (rhsTM) would...

Descripción completa

Detalles Bibliográficos
Autores principales: Iwashita, Yoshiaki, Zhang, Erquan, Maruyama, Junko, Yokochi, Ayumu, Yamada, Yasuharu, Sawada, Hirofumi, Mitani, Yoshihide, Imai, Hiroshi, Suzuki, Koji, Maruyama, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336269/
https://www.ncbi.nlm.nih.gov/pubmed/25705415
http://dx.doi.org/10.1186/s40560-014-0057-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336269/
https://www.ncbi.nlm.nih.gov/pubmed/25705415
http://dx.doi.org/10.1186/s40560-014-0057-0

Ejemplares similares