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Thrombomodulin protects against lung damage created by high level of oxygen with large tidal volume mechanical ventilation in rats
BACKGROUND: Ventilator-induced lung injury (VILI) is associated with inflammatory responses in the lung. Thrombomodulin (TM), a component of the coagulation system, has anticoagulant and anti-inflammatory effects. We hypothesized that the administration of recombinant human soluble TM (rhsTM) would...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336269/ https://www.ncbi.nlm.nih.gov/pubmed/25705415 http://dx.doi.org/10.1186/s40560-014-0057-0 |