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Thrombomodulin protects against lung damage created by high level of oxygen with large tidal volume mechanical ventilation in rats

BACKGROUND: Ventilator-induced lung injury (VILI) is associated with inflammatory responses in the lung. Thrombomodulin (TM), a component of the coagulation system, has anticoagulant and anti-inflammatory effects. We hypothesized that the administration of recombinant human soluble TM (rhsTM) would...

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Detalles Bibliográficos
Autores principales:	Iwashita, Yoshiaki, Zhang, Erquan, Maruyama, Junko, Yokochi, Ayumu, Yamada, Yasuharu, Sawada, Hirofumi, Mitani, Yoshihide, Imai, Hiroshi, Suzuki, Koji, Maruyama, Kazuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336269/ https://www.ncbi.nlm.nih.gov/pubmed/25705415 http://dx.doi.org/10.1186/s40560-014-0057-0

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