Effect of a selective neutrophil elastase inhibitor on mortality and ventilator-free days in patients with increased extravascular lung water: a post hoc analysis of the PiCCO Pulmonary Edema Study

BACKGROUND: Neutrophil elastase plays an important role in the development and progression of acute respiratory distress syndrome (ARDS). Although the selective elastase inhibitor, sivelestat, is widely used in Japan for treating ARDS patients, its effectiveness remains controversial. The aim of the...

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Detalles Bibliográficos
Autores principales: Tagami, Takashi, Tosa, Ryoichi, Omura, Mariko, Fukushima, Hidetada, Kaneko, Tadashi, Endo, Tomoyuki, Rinka, Hiroshi, Murai, Akira, Yamaguchi, Junko, Yoshikawa, Kazuhide, Saito, Nobuyuki, Uzu, Hideaki, Kase, Yoichi, Takatori, Makoto, Izumino, Hiroo, Nakamura, Toshiaki, Seo, Ryutarou, Kitazawa, Yasuhide, Sugita, Manabu, Takahashi, Hiroyuki, Kuroki, Yuichi, Irahara, Takayuki, Kanemura, Takashi, Yokota, Hiroyuki, Kushimoto, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336272/
https://www.ncbi.nlm.nih.gov/pubmed/25705423
http://dx.doi.org/10.1186/s40560-014-0067-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336272/
https://www.ncbi.nlm.nih.gov/pubmed/25705423
http://dx.doi.org/10.1186/s40560-014-0067-y

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