Activation of NOTCH1 or NOTCH3 Signaling Skews Human Airway Basal Cell Differentiation toward a Secretory Pathway

Airway basal cells (BC) function as stem/progenitor cells capable of differentiating into the luminal ciliated and secretory cells to replenish the airway epithelium during physiological turnover and repair. The objective of this study was to define the role of Notch signaling in regulating human ai...

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Detalles Bibliográficos
Autores principales: Gomi, Kazunori, Arbelaez, Vanessa, Crystal, Ronald G., Walters, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336283/
https://www.ncbi.nlm.nih.gov/pubmed/25700162
http://dx.doi.org/10.1371/journal.pone.0116507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336283/
https://www.ncbi.nlm.nih.gov/pubmed/25700162
http://dx.doi.org/10.1371/journal.pone.0116507

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