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Novel Receptor-Derived Cyclopeptides to Treat Heart Failure Caused by Anti-β(1)-Adrenoceptor Antibodies in a Human-Analogous Rat Model
Despite recent therapeutic advances the prognosis of heart failure remains poor. Recent research suggests that heart failure is a heterogeneous syndrome and that many patients have stimulating auto-antibodies directed against the second extracellular loop of the β(1) adrenergic receptor (β(1)EC2). I...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336331/ https://www.ncbi.nlm.nih.gov/pubmed/25700031 http://dx.doi.org/10.1371/journal.pone.0117589 |