Novel Receptor-Derived Cyclopeptides to Treat Heart Failure Caused by Anti-β(1)-Adrenoceptor Antibodies in a Human-Analogous Rat Model

Despite recent therapeutic advances the prognosis of heart failure remains poor. Recent research suggests that heart failure is a heterogeneous syndrome and that many patients have stimulating auto-antibodies directed against the second extracellular loop of the β(1) adrenergic receptor (β(1)EC2). I...

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Detalles Bibliográficos
Autores principales: Boivin, Valérie, Beyersdorf, Niklas, Palm, Dieter, Nikolaev, Viacheslav O., Schlipp, Angela, Müller, Justus, Schmidt, Doris, Kocoski, Vladimir, Kerkau, Thomas, Hünig, Thomas, Ertl, Georg, Lohse, Martin J., Jahns, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336331/
https://www.ncbi.nlm.nih.gov/pubmed/25700031
http://dx.doi.org/10.1371/journal.pone.0117589

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