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Microglial VPAC1R mediates a novel mechanism of neuroimmune-modulation of hippocampal precursor cells via IL-4 release

Neurogenesis, the production of new neurons from neural stem/progenitor cells (NSPCs), occurs throughout adulthood in the dentate gyrus of the hippocampus, where it supports learning and memory. The innate and adaptive immune systems are increasingly recognized as important modulators of hippocampal...

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Detalles Bibliográficos
Autores principales: Nunan, Robert, Sivasathiaseelan, Harri, Khan, Damla, Zaben, Malik, Gray, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336555/
https://www.ncbi.nlm.nih.gov/pubmed/24801739
http://dx.doi.org/10.1002/glia.22682