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1-Aminocyclopropanecarboxylic acid (ACPC) produces procognitive but not antipsychotic-like effects in rats

RATIONALE: In addition to the negative and positive symptoms of schizophrenia, cognitive deficits, including prefrontal cortical dysfunction, are now recognized as core features of this disorder. Compounds increasing the NMDA receptor function via the strychnine-insensitive glycine receptors have be...

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Detalles Bibliográficos
Autores principales: Popik, Piotr, Holuj, Malgorzata, Nikiforuk, Agnieszka, Kos, Tomasz, Trullas, Ramon, Skolnick, Phil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336651/
https://www.ncbi.nlm.nih.gov/pubmed/25260339
http://dx.doi.org/10.1007/s00213-014-3738-4