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Clinical implications of the quantitative detection of ID4 gene methylation in myelodysplastic syndrome

BACKGROUND: Myelodysplastic syndrome (MDS) eventually transforms into acute leukemia (AL) in about 30% of patients. Hypermethylation of the inhibitor of DNA binding 4 (ID4) gene may play an important role in the initiation and development of MDS and AL. The aim of this study was to quantitatively as...

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Detalles Bibliográficos
Autores principales: Kang, Huiyuan, Wang, Xinrong, Gao, Li, Cen, Jian, Li, Mianyang, Wang, Wei, Wang, Nan, Li, Yonghui, Wang, Lili, Yu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336702/
https://www.ncbi.nlm.nih.gov/pubmed/25889027
http://dx.doi.org/10.1186/s40001-015-0092-x