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The guanine exchange factor SWAP70 mediates vGPCR-induced endothelial plasticity

BACKGROUND: The viral G protein-coupled receptor (vGPCR) is proposed to act as one of the predominant mediators of Kaposi’s sarcoma (KS), a human herpes virus 8 (HHV8)-elicited disease. The actions of vGPCR manifest pathogenesis, in part, through increased permeability of endothelial cells. Endothel...

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Detalles Bibliográficos
Autores principales: Dwyer, Julie, Azzi, Sandy, Leclair, Héloïse M, Georges, Steven, Carlotti, Agnès, Treps, Lucas, Galan-Moya, Eva M, Alexia, Catherine, Dupin, Nicolas, Bidère, Nicolas, Gavard, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336709/
https://www.ncbi.nlm.nih.gov/pubmed/25889342
http://dx.doi.org/10.1186/s12964-015-0090-1