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Multiple myeloma cells alter the senescence phenotype of bone marrow mesenchymal stromal cells under participation of the DLK1-DIO3 genomic region

BACKGROUND: Alterations and senescence in bone marrow mesenchymal stromal cells of multiple myeloma patients (MM-BMMSCs) have become an important research focus. However the role of senescence in the pathophysiology of MM is not clear. METHODS: Correlation between senescence, cell cycle and microRNA...

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Detalles Bibliográficos
Autores principales: Berenstein, Rimma, Blau, Olga, Nogai, Axel, Waechter, Marlies, Slonova, Ekaterina, Schmidt-Hieber, Martin, Kunitz, Annegret, Pezzutto, Antonio, Doerken, Bernd, Blau, Igor Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336751/
https://www.ncbi.nlm.nih.gov/pubmed/25886144
http://dx.doi.org/10.1186/s12885-015-1078-3