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Breast and prostate cancer patients differ significantly in their serum Thymidine kinase 1 (TK1) specific activities compared with those hematological malignancies and blood donors: implications of using serum TK1 as a biomarker

BACKGROUND: Thymidine kinase 1 (TK1) is a cellular enzyme involved in DNA precursor synthesis, and its activity has been used as a proliferation marker for monitoring malignant diseases. Here, for the first time, we evaluated both TK1 activity and protein levels in sera from patients with different...

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Detalles Bibliográficos
Autores principales: Jagarlamudi, Kiran Kumar, Hansson, Lars Olof, Eriksson, Staffan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336758/
https://www.ncbi.nlm.nih.gov/pubmed/25881026
http://dx.doi.org/10.1186/s12885-015-1073-8