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Suppression of CYP2C9 by MicroRNA hsa-miR-128-3p in Human Liver Cells and Association with Hepatocellular Carcinoma

Published studies have identified genetic variants, somatic mutations, and changes in gene expression profiles that are associated with hepatocellular carcinoma (HCC), particularly involving genes that encode drug metabolizing enzymes (DMEs). CYP2C9, one of the most abundant and important DMEs, is i...

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Detalles Bibliográficos
Autores principales: Yu, Dianke, Green, Bridgett, Marrone, April, Guo, Yongli, Kadlubar, Susan, Lin, Dongxin, Fuscoe, James, Pogribny, Igor, Ning, Baitang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336941/
https://www.ncbi.nlm.nih.gov/pubmed/25704921
http://dx.doi.org/10.1038/srep08534