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TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury

BACKGROUND: Our previous study found that suppression of TRPM7 reduced neuronal death in adult rat ischemic brain injury. It was reported that carvacrol blocked TRPM7 and attenuated brain injury in an adult rat MCAO model. The effects of carvacrol on neonatal stroke remain unknown. This study invest...

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Detalles Bibliográficos
Autores principales: Chen, Wenliang, Xu, Baofeng, Xiao, Aijiao, Liu, Ling, Fang, Xiaoyan, Liu, Rui, Turlova, Ekaterina, Barszczyk, Andrew, Zhong, Xiao, Sun, Christopher L F, Britto, Luiz R G, Feng, Zhong-Ping, Sun, Hong-Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337201/
https://www.ncbi.nlm.nih.gov/pubmed/25761704
http://dx.doi.org/10.1186/s13041-015-0102-5