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Oncolytic tanapoxvirus expressing FliC causes regression of human colorectal cancer xenografts in nude mice

Colorectal cancers are significant causes of morbidity and mortality and existing therapies often perform poorly for individuals afflicted with advanced disease. Oncolytic virotherapy is an emerging therapeutic modality with great promise for addressing this medical need. Herein we describe the in v...

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Detalles Bibliográficos
Autores principales: Conrad, Steven J, El-Aswad, Mohamed, Kurban, Esaw, Jeng, David, Tripp, Brian C, Nutting, Charles, Eversole, Robert, Mackenzie, Charles, Essani, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337313/
https://www.ncbi.nlm.nih.gov/pubmed/25887490
http://dx.doi.org/10.1186/s13046-015-0131-z