Rare variant association studies: considerations, challenges and opportunities

Genome-wide association studies (GWASs) have successfully uncovered thousands of robust associations between common variants and complex traits and diseases. Despite these successes, much of the heritability of these traits remains unexplained. Because low-frequency and rare variants are not tagged...

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Detalles Bibliográficos
Autores principales: Auer, Paul L, Lettre, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337325/
https://www.ncbi.nlm.nih.gov/pubmed/25709717
http://dx.doi.org/10.1186/s13073-015-0138-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337325/
https://www.ncbi.nlm.nih.gov/pubmed/25709717
http://dx.doi.org/10.1186/s13073-015-0138-2

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