Cargando…

Homer2 deletion alters dendritic spine morphology but not alcohol-associated adaptations in GluN2B-containing N-methyl-D-aspartate receptors in the nucleus accumbens

Repeated exposure to ethanol followed by withdrawal leads to alterations in glutamatergic signaling and impaired synaptic plasticity in the nucleus accumbens (NAc) in both clinical and preclinical models of ethanol exposure. Homer2 is a member of a family of postsynaptic density (PSD) scaffolding pr...

Descripción completa

Detalles Bibliográficos
Autores principales: McGuier, Natalie S., Padula, Audrey E., Mulholland, Patrick J., Chandler, L. Judson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337331/
https://www.ncbi.nlm.nih.gov/pubmed/25755642
http://dx.doi.org/10.3389/fphar.2015.00028