Cargando…

Novel subcellular localization for α-synuclein: possible functional consequences

α-synuclein (α-syn) is one of the genes that when mutated or overexpressed causes Parkinson’s Disease (PD). Initially, it was described as a synaptic terminal protein and later was found to be localized at mitochondria. Mitochondria-associated membranes (MAM) have emerged as a central endoplasmic re...

Descripción completa

Detalles Bibliográficos
Autores principales: Guardia-Laguarta, Cristina, Area-Gomez, Estela, Schon, Eric A., Przedborski, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337379/
https://www.ncbi.nlm.nih.gov/pubmed/25755636
http://dx.doi.org/10.3389/fnana.2015.00017