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Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis

Despite their fundamental importance for body size regulation, the mechanisms that stop growth are poorly understood. In Drosophila melanogaster, growth ceases in response to a peak of the molting hormone ecdysone that coincides with a nutrition-dependent checkpoint, critical weight. Previous studie...

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Detalles Bibliográficos
Autores principales: Koyama, Takashi, Rodrigues, Marisa A, Athanasiadis, Alekos, Shingleton, Alexander W, Mirth, Christen K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337420/
https://www.ncbi.nlm.nih.gov/pubmed/25421296
http://dx.doi.org/10.7554/eLife.03091