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The PFA-AMeX method achieves a good balance between the morphology of tissues and the quality of RNA content in DNA microarray analysis with laser-capture microdissection samples

Recently, large-scale gene expression profiling is often performed using RNA extracted from unfixed frozen or formalin-fixed paraffin embedded (FFPE) samples. However, both types of samples have drawbacks in terms of the morphological preservation and RNA quality. In the present study, we investigat...

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Detalles Bibliográficos
Autores principales: Watanabe, Takeshi, Kato, Atsuhiko, Terashima, Hiromichi, Matsubara, Koichi, Chen, Yu Jau, Adachi, Kenji, Mizuno, Hideaki, Suzuki, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337499/
https://www.ncbi.nlm.nih.gov/pubmed/26023261
http://dx.doi.org/10.1293/tox.2014-0045