E6^E7, a Novel Splice Isoform Protein of Human Papillomavirus 16, Stabilizes Viral E6 and E7 Oncoproteins via HSP90 and GRP78

Transcripts of human papillomavirus 16 (HPV16) E6 and E7 oncogenes undergo alternative RNA splicing to produce multiple splice isoforms. However, the importance of these splice isoforms is poorly understood. Here we report a critical role of E6^E7, a novel isoform containing the 41 N-terminal amino...

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Detalles Bibliográficos
Autores principales: Ajiro, Masahiko, Zheng, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337564/
https://www.ncbi.nlm.nih.gov/pubmed/25691589
http://dx.doi.org/10.1128/mBio.02068-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337564/
https://www.ncbi.nlm.nih.gov/pubmed/25691589
http://dx.doi.org/10.1128/mBio.02068-14

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