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Inflammasome Activation in Response to the Yersinia Type III Secretion System Requires Hyperinjection of Translocon Proteins YopB and YopD

Type III secretion systems (T3SS) translocate effector proteins into target cells in order to disrupt or modulate host cell signaling pathways and establish replicative niches. However, recognition of T3SS activity by cytosolic pattern recognition receptors (PRRs) of the nucleotide-binding domain le...

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Detalles Bibliográficos
Autores principales: Zwack, Erin E., Snyder, Annelise G., Wynosky-Dolfi, Meghan A., Ruthel, Gordon, Philip, Naomi H., Marketon, Melanie M., Francis, Matthew S., Bliska, James B., Brodsky, Igor E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337566/
https://www.ncbi.nlm.nih.gov/pubmed/25691590
http://dx.doi.org/10.1128/mBio.02095-14