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Inflammasome Activation in Response to the Yersinia Type III Secretion System Requires Hyperinjection of Translocon Proteins YopB and YopD
Type III secretion systems (T3SS) translocate effector proteins into target cells in order to disrupt or modulate host cell signaling pathways and establish replicative niches. However, recognition of T3SS activity by cytosolic pattern recognition receptors (PRRs) of the nucleotide-binding domain le...
Autores principales: | Zwack, Erin E., Snyder, Annelise G., Wynosky-Dolfi, Meghan A., Ruthel, Gordon, Philip, Naomi H., Marketon, Melanie M., Francis, Matthew S., Bliska, James B., Brodsky, Igor E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337566/ https://www.ncbi.nlm.nih.gov/pubmed/25691590 http://dx.doi.org/10.1128/mBio.02095-14 |
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