A Single Phosphorodiamidate Morpholino Oligomer Targeting VP24 Protects Rhesus Monkeys against Lethal Ebola Virus Infection

Ebola viruses (EBOV) cause severe disease in humans and nonhuman primates with high mortality rates and continue to emerge in new geographic locations, including several countries in West Africa, the site of a large ongoing outbreak. Phosphorodiamidate morpholino oligomers (PMOs) are synthetic antis...

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Detalles Bibliográficos
Autores principales: Warren, Travis K., Whitehouse, Chris A., Wells, Jay, Welch, Lisa, Heald, Alison E., Charleston, Jay S., Sazani, Pete, Reid, St. Patrick, Iversen, Patrick L., Bavari, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337572/
https://www.ncbi.nlm.nih.gov/pubmed/25670780
http://dx.doi.org/10.1128/mBio.02344-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337572/
https://www.ncbi.nlm.nih.gov/pubmed/25670780
http://dx.doi.org/10.1128/mBio.02344-14

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