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Characterization of Host and Microbial Determinants in Individuals with Latent Tuberculosis Infection Using a Human Granuloma Model

Granulomas sit at the center of tuberculosis (TB) immunopathogenesis. Progress in biomarkers and treatment specific to the human granuloma environment is hindered by the lack of a relevant and tractable infection model that better accounts for the complexity of the host immune response as well as pa...

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Detalles Bibliográficos
Autores principales: Guirado, Evelyn, Mbawuike, Uchenna, Keiser, Tracy L., Arcos, Jesus, Azad, Abul K., Wang, Shu-Hua, Schlesinger, Larry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337582/
https://www.ncbi.nlm.nih.gov/pubmed/25691598
http://dx.doi.org/10.1128/mBio.02537-14