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Cofilin-induced unidirectional cooperative conformational changes in actin filaments revealed by high-speed atomic force microscopy

High-speed atomic force microscopy was employed to observe structural changes in actin filaments induced by cofilin binding. Consistent with previous electron and fluorescence microscopic studies, cofilin formed clusters along actin filaments, where the filaments were 2-nm thicker and the helical pi...

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Detalles Bibliográficos
Autores principales: Ngo, Kien Xuan, Kodera, Noriyuki, Katayama, Eisaku, Ando, Toshio, Uyeda, Taro QP
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337605/
https://www.ncbi.nlm.nih.gov/pubmed/25642645
http://dx.doi.org/10.7554/eLife.04806