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Activity and Ca(2+) regulate the mobility of TRPV1 channels in the plasma membrane of sensory neurons
TRPV1 channels are gated by a variety of thermal, chemical, and mechanical stimuli. We used optical recording of Ca(2+) influx through TRPV1 to measure activity and mobility of single TRPV1 molecules in isolated dorsal root ganglion neurons and cell lines. The opening of single TRPV1 channels produc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337616/ https://www.ncbi.nlm.nih.gov/pubmed/25569155 http://dx.doi.org/10.7554/eLife.03819 |