Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin

Extracellular signal-regulated kinase (ERK) is a key effector of many growth signalling pathways. In this study, we visualise epidermal ERK activity in living mice using an ERK FRET biosensor. Under steady-state conditions, the epidermis occasionally revealed bursts of ERK activation patterns where...

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Detalles Bibliográficos
Autores principales: Hiratsuka, Toru, Fujita, Yoshihisa, Naoki, Honda, Aoki, Kazuhiro, Kamioka, Yuji, Matsuda, Michiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337632/
https://www.ncbi.nlm.nih.gov/pubmed/25668746
http://dx.doi.org/10.7554/eLife.05178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337632/
https://www.ncbi.nlm.nih.gov/pubmed/25668746
http://dx.doi.org/10.7554/eLife.05178

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