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Distinct mechanisms regulating mechanical force-induced Ca(2+) signals at the plasma membrane and the ER in human MSCs

It is unclear that how subcellular organelles respond to external mechanical stimuli. Here, we investigated the molecular mechanisms by which mechanical force regulates Ca(2+) signaling at endoplasmic reticulum (ER) in human mesenchymal stem cells. Without extracellular Ca(2+), ER Ca(2+) release is...

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Detalles Bibliográficos
Autores principales: Kim, Tae-Jin, Joo, Chirlmin, Seong, Jihye, Vafabakhsh, Reza, Botvinick, Elliot L, Berns, Michael W, Palmer, Amy E, Wang, Ning, Ha, Taekjip, Jakobsson, Eric, Sun, Jie, Wang, Yingxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337650/
https://www.ncbi.nlm.nih.gov/pubmed/25667984
http://dx.doi.org/10.7554/eLife.04876