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Bridged filaments of histone-like nucleoid structuring protein pause RNA polymerase and aid termination in bacteria

Bacterial H-NS forms nucleoprotein filaments that spread on DNA and bridge distant DNA sites. H-NS filaments co-localize with sites of Rho-dependent termination in Escherichia coli, but their direct effects on transcriptional pausing and termination are untested. In this study, we report that bridge...

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Detalles Bibliográficos
Autores principales: Kotlajich, Matthew V, Hron, Daniel R, Boudreau, Beth A, Sun, Zhiqiang, Lyubchenko, Yuri L, Landick, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337669/
https://www.ncbi.nlm.nih.gov/pubmed/25594903
http://dx.doi.org/10.7554/eLife.04970