Population pharmacokinetics of pegaptanib sodium (Macugen(®)) in patients with diabetic macular edema

OBJECTIVE: Population pharmacokinetic modeling of pegaptanib was undertaken to determine influence of renal function on apparent clearance. METHODS: In a randomized, double-masked multicenter trial, intravitreal pegaptanib (0.3, 1.0, or 3.0 mg/eye) was administered in patients with diabetic macular...

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Detalles Bibliográficos
Autores principales: Basile, Anthony S, Hutmacher, Matthew M, Kowalski, Kenneth G, Gandelman, Kuan Y, Nickens, Dana J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337691/
https://www.ncbi.nlm.nih.gov/pubmed/25733800
http://dx.doi.org/10.2147/OPTH.S74050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337691/
https://www.ncbi.nlm.nih.gov/pubmed/25733800
http://dx.doi.org/10.2147/OPTH.S74050

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