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Population pharmacokinetics of pegaptanib sodium (Macugen(®)) in patients with diabetic macular edema

OBJECTIVE: Population pharmacokinetic modeling of pegaptanib was undertaken to determine influence of renal function on apparent clearance. METHODS: In a randomized, double-masked multicenter trial, intravitreal pegaptanib (0.3, 1.0, or 3.0 mg/eye) was administered in patients with diabetic macular...

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Detalles Bibliográficos
Autores principales:	Basile, Anthony S, Hutmacher, Matthew M, Kowalski, Kenneth G, Gandelman, Kuan Y, Nickens, Dana J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337691/ https://www.ncbi.nlm.nih.gov/pubmed/25733800 http://dx.doi.org/10.2147/OPTH.S74050

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