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The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
Autophagy is a fundamental adaptive response to amino acid starvation orchestrated by conserved gene products, the autophagy (ATG) proteins. However, the cellular cues that activate the function of ATG proteins during amino acid starvation are incompletely understood. Here we show that two related s...
Autores principales: | Wei, Yongjie, An, Zhenyi, Zou, Zhongju, Sumpter, Rhea, Su, Minfei, Zang, Xiao, Sinha, Sangita, Gaestel, Matthias, Levine, Beth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337728/ https://www.ncbi.nlm.nih.gov/pubmed/25693418 http://dx.doi.org/10.7554/eLife.05289 |
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