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Eye morphogenesis driven by epithelial flow into the optic cup facilitated by modulation of bone morphogenetic protein

The hemispheric, bi-layered optic cup forms from an oval optic vesicle during early vertebrate eye development through major morphological transformations. The overall basal surface, facing the developing lens, is increasing, while, at the same time, the space basally occupied by individual cells is...

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Detalles Bibliográficos
Autores principales: Heermann, Stephan, Schütz, Lucas, Lemke, Steffen, Krieglstein, Kerstin, Wittbrodt, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337729/
https://www.ncbi.nlm.nih.gov/pubmed/25719386
http://dx.doi.org/10.7554/eLife.05216