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Isovaline Does Not Activate GABA(B) Receptor-Coupled Potassium Currents in GABA(B) Expressing AtT-20 Cells and Cultured Rat Hippocampal Neurons
Isovaline is a non-proteinogenic amino acid that has analgesic properties. R-isovaline is a proposed agonist of the γ-aminobutyric acid type B (GABA(B)) receptor in the thalamus and peripheral tissue. Interestingly, the responses to R-isovaline differ from those of the canonical GABA(B) receptor ago...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337901/ https://www.ncbi.nlm.nih.gov/pubmed/25706125 http://dx.doi.org/10.1371/journal.pone.0118497 |